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Clinical studies with colchicine for prophylaxis and treatment of gout flares and for treatment of FMF did not include sufficient numbers of patients aged 65 years and older to determine whether they respond differently from younger patients.

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By reducing the amount of white blood cells, Colcrys helps to break the cycle of inflammation; thereby causing a reduction in the swelling and pain.

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Administration of COLCRYS with food has no effect on the rate of colchicine absorption but does decrease the extent of colchicine by approximately 15%.

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Criteria have been established for the diagnosis of Behcet's disease, but these aren't always essential for the diagnosis of the disease.

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Patients with diabetes should be regularly monitored for worsening of glucose control; those with risk factors for diabetes should undergo baseline and periodic fasting blood glucose testing.

You should not take colchicine during your treatment with amoxicillin, clarithromycin, and omeprazole, especially if you are an older adult with kidney disease.

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This is particularly the case when very sensitive techniques (eg real-time PCR) are used on specimens originating from so-called “privileged sites” like semen, vitreous fluid etc.

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If you are taking colchicine regularly and miss a dose, take it as soon as you remember.

Uric acid has a role in protecting DNA from single-strand breaks caused by free radicals in the body leading to a protective effect in neurodegenerative diseases.

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Long-term (prophylactic) regimens of oral colchicine are absolutely contraindicated in patients with advanced renal failure (including those on dialysis).

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